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• amphetamine, dextroamphetamine or cocaine
• dihydroergotamine, ergotamine, ergoloid mesylates, methysergide, or ergot-type medication - do not take within 24 hours of taking rizatriptan
• feverfew
• MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate - do not take rizatriptan within 2 weeks of stopping MAOI therapy.
• other migraine medicines like almotriptan, eletriptan, naratriptan, sumatriptan, zolmitriptan - do not take within 24 hours of taking rizatriptan
• tryptophan

Maxalt may also interact with the following:

• medicines for mental depression, anxiety or mood problems
• propranolol

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